Folks in every generation start to believe there is nothing yet to discover. In the 1800s, this was so, and that pattern continues. However, things are yet to be learned about, discovered, and invented.
Quantum Gravity. The biggest unsolved problem in fundamental physics is how gravity and the quantum will be made to coexist within the same theory. ...
Particle Masses. ...
The “Measurement” Problem. ...
Turbulence. ...
Dark Energy. ...
Dark Matter. ...
Complexity. ...
The Matter-Antimatter.
Turbulence-tossing aircraft that injured people have been happening more often (it seems so, anyway). If someone could discover how to detect or predict this phenomenon, it would be an excellent service to aircraft travelers. Perhaps an algorithm for interpreting weather radar data that most planes gather and process. Yes, there are some logical predictions like storms, but the most daunting and dangerous turbulence is "clear air turbulence."
I have learned that in the world of kinky things, humans have become highly inventive, so I know that there are reasonable minds in the community that may be able to address this problem. Whoever solves this a $1,000,000.00 prize will be offered by (... a cash
prize of $1,000,000 from Clay Institute.)